Immunology, Infection, and Immunity

Author: Gerald B. Bryan Pier
Published: April 2004
Publisher: ASM Press
ISBN: 1555812465
Hardcover Book
Number of Pages: 742

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Ideally suited for upper-division and graduate-level biology students as well as medical and dental students with a good background in basic biology, biochemistry, genetics, and cell biology, this book will also appeal to scientists seeking to expand their knowledge of immunology. With a focus on the relatedness of immunology and microbiology, Immunology, Infection, and Immunity covers both the foundation concepts of immunology, among the most exciting in modern biology and medicine, and their application to the real world of diseases and health. This new text combines clear narratives of how the immune system functions, relying in many instances on supporting data from experiments. Examples and illustrations depict basic immunologic processes in conjunction with their role in infectious or other diseases in order to teach both basic and applied aspects of immunology. In addition to an emphasis on infectious diseases, the book focuses strongly on those areas where the immune system does not act when it should as well as areas where the overactivity or dysregulation of the immune system is a cause of pathology. To bring the full flavor and excitement of immunology to new students, the editors have assembled an outstanding group of contributors with expertise in multiple areas of immunology who provide the most up-to-date information in this quickly moving field. This textbook for undergraduate biology and medical students describes the basic molecular and cellular components of the immune system, the pathogenesis and prevention of infectious diseases, and common immune system dysfunctions. Topics of the 27 chapters include antibodies, the major histocompatibility complex, antigen processing, the T-cell receptor, vaccines, AIDS, and transplantation immunology. Color illustrations depict the immunologic processes in conjunction with their role in infectious or other diseases. Annotation © 2004 Book News, Inc., Portland, OR

Table of Contents
Ch. 1 Overview of immunity 3
Ch. 2 Innate immunity 29
Ch. 3 Cells of the immune system 47
Ch. 4 Organs and tissues of the immune system 67
Ch. 5 Complement 85
Ch. 6 Antibodies 113
Ch. 7 Molecular genetics of antibody diversity 145
Ch. 8 Antigens, antigenicity, and immunogenicity 185
Ch. 9 Antibody-antigen interactions and measurements of immunologic reactions 207
Ch. 10 B-lymphocyte activation and antibody production 233
Ch. 11 The major histocompatibility complex 261
Ch. 12 Antigen processing and presentation 283
Ch. 13 The T-cell receptor 297
Ch. 14 T-cell maturation and activation 315
Ch. 15 Cellular communication 343
Ch. 16 Cell-mediated immunity 373
Ch. 17 Mucosal immunity 399
Ch. 18 Immunity to bacterial infections 425
Ch. 19 Immunity to viruses 453
Ch. 20 Immunity to parasitic and fungal infections 469
Ch. 21 Vaccines and vaccination 497
Ch. 22 Immunology and AIDS 531
Ch. 23 Clinical and genetic perspectives in primary immunodeficiency disorders 553
Ch. 24 Cancer and the immune system 573
Ch. 25 Hypersensitivity 595
Ch. 26 Autoimmunity and disease 625
Ch. 27 Transplantation immunology 649
App. A CD antigens 667
App. B Antigen names with CD designation equivalents 675
App. C Cytokines, chemokines, and their receptors 681
App. D Cell types and immune-related functions 689
App. E Historical timeline of immunology 691
App. F Time course of a typical immune response 693
App. G Comparison of relative sizes of cells, structures, and molecules that are relevant to infection and immunity 695

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