Betrayal by the Brain: The Neurologic Basis of Chronic Fatigue Syndrome, Fibromyalgia Syndrome, and Related Neural Network Disorders
Author: Jay A. Goldstein Published: January 1996 Publisher: Haworth Press, Incorporated ISBN: 1560249773 Hardcover Book Number of Pages: 313
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In his trademark, revolutionary style, Dr. Goldstein uses his model of neural dysregulation to incorporate basic neuroscience research into pathophysiology and treatment. Betrayal by the Brain presents a comprehensive thesis that clearly defines the biological basis for many of the varied symptoms experienced by chronic fatigue syndrome patients. Dr. Goldstein provides a rationale for the use of symptomatic therapies that have worked in many CFS patients. Betrayal by the Brain is a valuable handbook to assist the medical professional in the diagnosis and treatment of the many patients afflicted with this illness. This new book, written by a practitioner in the field, is a review of the author's take on the literature of chronic fatigue syndrome (CFS) and fibromyalgia (FMS). The author emphasizes the biochemical neural network dysfunction in relation to these ailments. The purpose of this book is essentially to explain Dr. Goldstein's theory of the pathogenesis and treatment of CFS and FMS to the reader and to justify the various treatments he uses. The intended audience, although not specifically stated, is physicians who deal with chronic fatigue and fibromyalgia patients. The book includes an introduction from the author, his treatment protocol, a review of FMS, a review of CFS, a review of cerebellar and basal ganglia functions in relation to these disorders, sleep and arousal systems, a review of irritable bowel syndrome, receptor desensitization and drug tolerance, treatments, a conclusion section, references, and an index section. The chapters usually include case studies. I had problems with this book. The author seems quite knowledgeable and has the ability to synthesize a vast array of literature, but the book is filled with, I believe, idiosyncratic ideas and idiosyncratic treatment recommendations. Case reports have the lowest of scientific validity; they just present the numerator without the denominator. It behooves Dr. Goldstein to either find the funding to do the double-blind controlled studies or fund it himself. Written as a companion volume to Chronic Fatigue Syndromes: The Limbic Hypothesis, and intended as a handbook to assist in the diagnosis and treatment of this and other neurologic disorders. Discusses a typical neurosomatic new patient treatment protocol, CFS pathophysiology, fibromyalgia syndrome as a pain modulation disorder, the roles of the cerebellum and basal ganglia in neural network dysfunction, sleep and arousal generating systems, irritable bowel syndrome, receptor desensitization and drug tolerance, and treatments. Paper edition (981-1), $29.95.
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