Environmental Endocrine Disruptors

Author: Louis J. Guillette
Published: August 2000
Publisher: CRC Press
ISBN: 1560325712
Hardcover Book
Number of Pages: 355

Click to compare book prices for Environmental Endocrine Disruptors

Environmental Endocrine Disrupters presents the latest research in reproductive toxicology. This book focuses on endocrine disruption by contaminants in humans, other mammals, and other vertebrates. Specifically, it addresses the problem of endocrine disrupting contaminants (EDCs) from an evolutionary comparative perspective. It provides a background on the evolution of the vertebrate endocrine system, as well as the evolution of vertebrate systems associated with lipid storage and utilization. (Many EDCs are stored in and released from fat stores.) Specific aspects of the EDC problem include effects on the reproductive, immune, and nervous systems and Guillette also examines the liver and thyroid. Each chapter explores the evolution of endocrine signaling and the comparative nature of the supporting data and separates the role of EDCs in adults from developing embryos.

Table of Contents:

Preface
Acknowledgments
Ch. 1 Endocrine-Disrupting Contaminants and Hormone Dynamics: Lessons from Wildlife 1
Ch. 2 The Importance of Comparative Endocrinology in Examining the Endocrine Disrupter Problem 22
Ch. 3 Bioaccumulation, Storage, and Mobilization of Endocrine-Altering Contaminants 52
Ch. 4 Contaminant Interactions with Steroid Receptors: Evidence for Receptor Binding 82
Ch. 5 Steroid Hormone-Regulated Processes in Invertebrates and their Susceptibility to Environmental Endocrine Disruption 126
Ch. 6 Contaminant-Altered Thyroid Function in Wildlife 155
Ch. 7 Biomarkers of Immunotoxicity: An Evolutionary Perspective 182
Ch. 8 Ethotoxicology: An Evolutionary Approach to Behavioral Toxicology 217
Ch. 9 Embryonic and Neonatal Exposure to Endocrine-Altering Contaminants: Effects on Mammalian Female Reproduction 234
Ch. 10 Endocrine Disruption in Male Human Reproduction 269
Ch. 11 Xenoestrogens in the Context of Carcinogenesis 291
Ch. 12 An Anthropological Interpretation of Endocrine Disruption in Children 322
Index 339

Click to compare book prices for Environmental Endocrine Disruptors Environmental Endocrine Disruptors

Compare Shop Books - Help - About - Book Links - Book Coupons