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New authors were recruited to make the second edition not only more current than the first, for which no date is cited, but also broader in its coverage of the pathophysiology, clinical presentation, and treatment of thyroid disease. Specialists mostly from the US consider neonatal thyroid screening, thyroid dysfunction during infancy and childhood, peripartum thyroid disorders, the elderly, the clinical relevance of the sodium/iodide symporter to pathogenesis and treatment, the worldwide iodine deficiency and its eradication, and other topics.

Table of Contents:

Preface
Contributors
1 Molecular Mechanisms of Nuclear Thyroid Hormone Action 1
2 Nongenomic Actions of Thyroid Hormone 19
3 Thyroid Testing: A Clinical Approach 39
4 Neonatal Screening for Thyroid Disease 53
5 Thyroid Disease in Infancy, Childhood, and Adolescence 63
6 Thyroid Disease in Older Persons 85
7 Autoimmune Thyroid Diseases 107
8 Problems in the Management of Hypothyroidism 161
9 Management of the Various Causes of Thyrotoxicosis 177
10 Resistance to Thyroid Hormone 199
11 Evaluation and Management of the Euthyroid Nodular and Diffuse Goiter 217
12 Radiation and Thyroid Cancer: Lessons from a Half Century of Study 239
13 Management of Thyroid Cancer 263
14 Thyroid Dysfunction During Pregnancy and After Delivery 291
15 Goitrogens in the Environment 307
16 Iodine Deficiency and Its Elimination by Iodine Supplementation 329
17 Iodine-Induced Thyroid Disease 347
18 Clinical Relevance of the Thyroid Sodium/Iodide Symporter 363
Index 377