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Preface
Molecular Genetics - Ethical and Political Questions 1
Fetal-Maternal Amino Acid Relationships in Normal and Intrauterine Growth Retarded (IUGR) Pregnancies 11
Human Placental Transport and Metabolism of All-Trans Retinoic Acid In Vitro 25
Transport and Metabolism of Monoamines in the Human Placenta - A Review - 35
Patch Clamp Studies of Human Placental Cytotrophoblast Cells in Culture 53
Placental Metabolism and Transport of Amino Acids and Glucose - A Workshop Report - 69
Placental Permeability and Electrolyte Transport - A Workshop Report - 71
Mitochondrial Glutamine and Glutamate Metabolism in Human Placenta and its Possible Link with Progesterone Biosynthesis 77
Metabolism of Glutamic Acid Studied in the Dually In Vitro Perfused Human Placental Cotyledon 87
Placenta-Fetal "Alanine-Lactate Cycle" in the Human During Late Gestation 103
Novel Endothelial-Derived Vasoactive Factors in the Human Fetal-Placental Circulation 117
Effects of Eicosanoid and Endothelial Cell Derived Relaxing Factor Inhibition on Fetal Vascular Tone and Responsiveness in the Human Perfused Placenta 133
Alterations in Prostaglandin Metabolism of Cultured Human Umbilical Vein Endothelial Cells Affected by Smoking During Pregnancy 147
Atrial Natriuretic Peptide: A New Hormone in the Fetoplacental Arterial Circulation 157
Troph-uteronectin (TUN): A Unique Oncofetal Fibronectin Deposited in the Extracellular Matrix of the Tropho-Uterine Junction and Regulated In Vitro by Cultured Human Trophoblast Cells 167
Differentiation of Human Trophoblast Cells In Vitro Stimulated by Extracellular Matrix 181
Role of Extracellular Matrix in Regulation of Type IV Collagenase Synthesis by Human Trophoblast Cells and Their Malignant Counterparts 201
Trophoblast-Endometrium Co-Cultures as a Means of Assessment of Endometrial Readiness for Implantation 211
Tissue Interactions in First Trimester Trophoblast-Decidua Co-Cultures 223
Molecular Mechanisms Controlling Trophoblast Invasion of the Uterus 237
Growth Factors in the Biology of Human Trophoblast and Their Clinical Relevances in Early Pregnancy Maintenance 251
Placental Dynamic Cultures - A Workshop Report - 265
Trophoblastic Localization of [[superscript 125]I] Endothelin-1 Binding Sites in Human Placenta 271
Expression and Control of PDGF Stimulatory Loops in the Developing Placenta 287
List of Contributors 305
Index 313