The Scientific Basis of Urology

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Author: Anthony R. Mundy
Published: July 2003
Publisher: Taylor & Francis, Inc.
ISBN: 1901865134
Hardcover Book
Number of Pages: 670

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The Scientific Basis of Urology

Written specifically for urological trainees by a distinguished team of contributors, this book provides the reader with a thorough coverage of the scientific basis of urology. Every area, function, illness and cure of the urinary tract, along with specific discussions of the relevant anatomy and physiology, is covered in clearly written text, abundantly illustrated with full colour photographs and diagrams. Each chapter takes the basic principles of its area of coverage and expands upon them to enable the reader to come fully to grips with the subject. This up-to-date reference provides a broad coverage of the major areas of urology faced by a practising or training urologist. This book provides an introduction to many broad topics in urology. Presented in a easy to read format, the goal is to provide the basic science principles as a foundation to understanding many clinical aspects of urology while at the same time providing a reference for practicing urologists. This book is aimed at providing urology residents with the fundamental knowledge they will need during their urologic training. Many areas of the text appear to be much more clinically oriented than one might expect from the title and the stated intent of this book. For example, in the chapter on the scientific basis of calcium oxalate stone formation, there is a paucity of information regarding the metabolism or chemistry of calcium oxalate, but multiple reviews of studies which emphasize the controversy that exists in urolithology. Other chapters such as "Testis Cancer" are more complete and do achieve the stated goals. Some areas of urology, such as pediatric urology and infertility, are covered in only a cursory fashion, although many other areas, such as physiology of both the upper and lower urinary tracts, are very complete. The illustrations, graphs, and pictures in the text are excellent and for the most are helpful in providing summaries and additional information to the teachings in the chapter. There is an easy to use index that provides quick references to specific topics covered by the text, although references at the end of the chapters were provided in an inconsistent manner between a "further reading" list and traditional references. The book provides a quick, easy to read guide useful for medical students, a reference for clinical urologists in practice, and perhapsbeginning urology residents, but lacks the depth to cover the basic science principles needed to be acquired by urologic residents during the training to prepare for board examinations. Mundy, Anthony R. (Institute of Urology and Nephrology, London); Fitzpatrick, John M. (Univ Coll Dublin); Neal, David E. (Univ of Newcastle upon Tyne); George, Nicholas J.R. (Withington Hospital, Manchester)

Table of Contents
1 An introduction to cell biology 1
2 The cell and cell division 31
3 Inflammation 57
4 Immunology 67
5 The nature of renal function 83
6 Principles of radiological imaging of the urinary tract 117
7 Upper urinary tract obstruction 129
8 Interactive obstructive uropathy : observations and conclusions from studies on humans 147
9 Urinary tract infection 165
10 The scientific basis of urinary stone formation 205
11 Shock 229
12 Acute renal failure 245
13 Chronic renal failure 257
14 Structure and function of the lower urinary tract 265
15 Detrusor smooth muscle physiology 291
16 The pathophysiology of bladder dysfunction 315
17 The scientific basis of urodynamics 327
18 Male sexual function 343
19 The prostate and benign prostatic hyperplasia 367
20 Biology of cancer and metastasis 387
21 Tumour suppressor genes and oncogenes 395
22 The molecular genetics and pathology of renal cell carcinoma 407
23 Transitional cell carcinoma of the bladder 431
24 Prostate cancer 449
25 Testis cancer 469
26 Radiotherapy : scientific principles and practical application in urological malignancies 493
27 Principles of chemotherapy 507
28 Embryology 521
29 Urological and biochemical aspects of transplantation biology 539
30 Tissue transfer in urology 549
31 Energy sources in urology 561
32 Urological instrumentation 579
33 Perioperative care of the urological patient 589
34 Screening in urology 607
35 The design, construction and interpretation of clinical trials 625
36 Evidence-based medicine for urologists 635

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