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Impact of Endogenous and Exogenous Factors on Radiation Sequelae 3
Endogenous and Exogenous Factors Modifying Chemosensitivity to Cytostatic Drugs 13
Radiation-Induced Injury of the Central Nervous System 23
Cytostatic-Induced Central Nervous System Abnormalities 29
Radiation Myelopathy 35
Acute and Late Toxicity on Peripheral Nerves After Radiotherapy 43
Acute and Late Toxicity on Peripheral Nerves After Chemotherapy - A Review 51
Endocrine Dysfunction After Brain Tumor Therapy in Children 59
Endocrine Dysfunction in Adults After Radiotherapy for Pituitary Adenomas and Suprasellar Tumors 65
Late Sequelae Affecting the Ear 73
Ototoxicity in Pediatric Oncology 81
Biological Basis for Skin and Mucosal Toxicity 89
Radiation-Induced Fibrosis: Experimental Studies 93
Lymphedema of the Arm After Treatment of Breast Cancer 99
Skin and Mucosal Damage After Radiotherapy for Head and Neck Tumors 105
Mucosal Toxicity After Radiochemotherapy 111
Complications of the Small Intestine and the Pancreas After Intraoperative Radiotherapy 121
Skin Toxicity 127
Radiation Pneumopathy - Experimental and Clinical Data 135
Lung Toxicity of Chemotherapeutic Agents 141
Differential Diagnosis of Treatment Sequelae in the Lung 151
Evaluation of Late Cardiotoxicity by Pulsed Doppler Echocardiography in Patients Treated for Hodgkin's Disease 163
Anthracycline-Induced Cardiotoxicity in Children: Pathophysiology and Prevention 175
Radiation-Induced Cardiotoxicity: Experimental Data 181
Cardiotoxicity After Megavoltage Irradiation and Chemotherapy for Hodgkin's Disease with Special Emphasis on Coronary Heart Disease Mortality - The Freiburg Experience 1940-1992 191
Cardiac Morbidity and Mortality Following Radiotherapy 197
Nephrotoxicity of Ifosfamide in Children 207
Radiation Nephritis 215
Long-Term Gonadal Dysfunction and Its Impact on Bone Mineralization in Patients Following COPP/ABVD Chemotherapy for Hodgkin's Disease 227
Gonadal Dysfunction After Radiotherapy 235
Dose-Time Considerations for Skeletal Growth Disturbances After Radiotherapy 245
Disturbances in Growth of Bone, Muscle, and Fat Tissue Following Irradiation in Childhood 251
Growth Failure Secondary to Radiotherapy of Brain Tumors in Childhood 255
Experiments on the Carcinogenic Potential of Antineoplastic Agents 263
Secondary Malignancies Following Cytotoxic Chemotherapy 273
Secondary Malignancies After Radiotherapy 279
Subject Index 291
List of Contributors 295