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Preface
HIV-1 Infection in Humans
T Cell Heterogeneity and HIV Infection 1
HIV-TNF Interactions in Virgin and Memory CD4+ T Cells 10
Lymphocyte Functional Analysis in HIV Infection: Mechanisms and Pathogenic Relevance 22
Quantitating the HIV-1-Specific Cytotoxic T Cell Response 30
Alveolar Cytotoxic T Lymphocytes Specific for HIV in HIV-Related Lung Diseases 40
Cytotoxic T Cell Response to HIV-1 and HTLV-1: Issues of Protection and Pathogenesis 49
Longitudinal Study of HIV gag-Specific Cytotoxic T Lymphocyte Responses over Time in Several Patients 60
Analysis of HIV-1 gag Peptides with a Quantitative Peptide-Dependent Class I Assembly Assay 66
Characterization of the Cytotoxic Immune Responses to HIV-1 81
SIV and HIV-2 Infection in Experimental Animals
The CD8+ Lymphocyte Response in Simian Immunodeficiency Virus-Infected Rhesus Monkeys 86
Detection of gag-Specific Cytotoxic T Lymphocytes in HIV-2[actual symbols not reproducible]-Infected Macaques 103
Immunostimulating Complexes Allow the in vivo Immunisation of Class I MHC-Restricted Murine CD8+ Cytolytic T Lymphocytes towards Soluble Antigens 114
T Lymphocyte Subpopulation and Cytokine Expression in Tissues
T Lymphocyte Subpopulations and Endothelial Cell Activation in Persistent Generalized Lymphadenopathy of HIV-Positive Patients 118
HIV-1 Regulatory Protein Expression in Tissues of Infected and Uninfected Individuals 130
Detection of Serine Esterase Granzyme B as Indicator of Cytotoxic Cells in Lymphoid Follicles of Man and Cynomolgus Monkeys after HIV-1/SIV Infection 140
Cytokine Expression and Its Possible Involvement in Lymphoma Induction and Progression 150
CD8+ Lymphocyte Response in Lymph Nodes from Patients with HIV Infection 162
Subject Index 175