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Animal Models of HIV and Other Retroviral Infections

Author: Paul Racz
Published: August 1993
Publisher: Karger, S. Inc.
ISBN: 3805556772
Hardcover Book
Number of Pages: 200
 
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Animal Models of HIV and Other Retroviral Infections


Table of Contents:


Preface
Latency in Lentiviral Infections: Analysis by Polymerase Chain Reaction in situ 1
Immune Responsiveness against the V3 Loop of HIV-1 gp120 and Animal Models 10
The T Lymphocyte Response to HIV: Molecular Basis for Immune Recognition and Escape 20
The Role of Cytotoxic T Lymphocytes in the Immunopathogenesis of SIV-Induced Disease 24
Pathogenic Mechanisms in HIV and SIV Infections 39
Pathology of the Lymphoid System in Cynomolgus Monkeys Infected with SIV[subscript sm] 49
The Thymus in SIV Infection
Cellular and Humoral Immune Responses to Poliovirus and Tetanus following Primary Immunization of SIV Infected Macaques 75
Induction of T Cell Proliferation in Rhesus Macaques Immunized with Tween-Ether-Treated SIV[subscript mac] and Loss of Proliferative Activity after Virus Infection 86
HIV-2 in Rhesus Monkeys: Five-Year Follow-Up 95
Pathogenesis of Feline Immunodeficiency Virus Infection 108
Morphologic Characterization of the Lymph Node Changes in Feline Immunodeficiency Virus Infection as an Animal Model of AIDS 115
Characterization of Feline Leukemia Virus Infection as an Animal Model of AIDS 137
CD4 T Cell Depletion in hu-PBL-SCID Mice by Noncytopathic HIV Isolates 164
Detection by Polymerase Chain Reaction of HIV-1 gag Sequences in Cells and Organs of Infected Rabbits 171
Role of the Immune Response in Visna, a Lentiviral Central Nervous System Disease of Sheep 183
Subject Index 196


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Animal Models of HIV and Other Retroviral Infections





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