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Introduction
Retrobulbar Histology and Immunohistochemistry in Endocrine Ophthalmopathy 1
Immunogenetics of Endocrine Ophthalmopathy and Graves' Disease 11
T Cell Reactivity in Endocrine Ophthalmopathy 20
Biological Activity of Antibodies Circulating in Endocrine Ophthalmopathy 29
Elevated Anti-Alpha-Galactosyl Antibody Titres: A Marker of Progression in Endocrine Ophthalmopathy and in Auto-Immune Thyroid Disorders 38
Orbital Connective Tissue in Endocrine Ophthalmopathy 46
Urinary and Plasma Glycosaminoglycans in Endocrine Ophthalmopathy 58
Adipose Tissue in Endocrine Ophthalmopathy 68
Nature and Significance of Eye Muscle Autoantigens in Endocrine Ophthalmopathy 77
Back to the Drawing Board for Antigens in Endocrine Ophthalmopathy 86
Eye Muscle Cells in Endocrine Ophthalmopathy 93
Graves' Hyperthyroidism and Endocrine Ophthalmopathy - One or Two Closely Related Diseases? 101
Autoimmune Endocrine Ophthalmopathy - The Ophthalmologist's View 112
Immunosuppression in Endocrine Ophthalmopathy: Why and When? 120
Orbital Radiotherapy in the Treatment of Endocrine Ophthalmopathy: When and Why? 131
Orbital Decompression for Endocrine Ophthalmopathy: The Endonasal Approach 142
Subject Index 151
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