Immunological Alterations in Psychiatric Diseases: International Symposium, Reisensburg, September 1995

Author: A. E. Henneberg
Published: February 1997
Publisher: Karger, S. Inc.
ISBN: 3805563841
Hardcover Book
Number of Pages: 117

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During the past three decades psychiatric research has made use of the expertise and techniques of many medical disciplines, among them neuroendocrinology, immunology, virology, genetics, and molecular biology. This book provides a concise overview of our present knowledge on the immunological aspects of psychiatric diseases, in particular schizophrenia, drug addiction and Alzheimer's disease. In addition, fundamental questions concerning the bi-directional interactions between the central nervous system and the immune system are discussed and the role of viruses and infectious processes closely examined. As such, this book offers a unique presentation of the state of the art in psychoimmunology and, at the same time, shows many important challenges for future research into the field of intersystemic interactions and their impact on the etiology and pathogenesis of psychiatric diseases. Psychiatrists and neurologists will gain a better understanding of the biological basis of psychiatric diseases while immunologists, neuroimmunologists, neurobiologists, neuroendocrinologists and virologists will find it a valuable source of new information on psychoimmunology research.

Table of Contents
Dedication
Preface
Viruses as Etiologic Agents of Schizophrenia 1
Is There an Immunopathology of the Serotonergic Synapse in Mental Disorder? 13
Dependence of Human Cytokine Production and Mononuclear Cell Subset Counts on Circadian Rhythm and Sleep 18
Opiate Addiction and Immunology 32
Clinical and Immunological Characteristics of a Subgroup of Patients Suffering from Schizophrenia 35
Relapse Prediction in Schizophrenia: From Monoamines to Cytokines 44
Interferons in Schizophrenia 50
Interferon-[gamma] in Schizophrenia 57
T-Cell Subsets in Schizophrenic Patients 67
Cytological Aberrations in the Cerebrospinal Fluid and Peripheral Blood of Schizophrenic Patients 72
Immunological Effects of Treatment in Schizophrenia 78
Immunological Factors in the Sera of Patients with Acute and Chronic Schizophrenia 85
Single-Photon Emission Computed Tomography Findings in Schizophrenia 90
Schizophrenia, Genetics, Autoimmunity: Contradictions and Explanations 96
Chronic Schizophrenia and Alzheimer's Disease from the Viewpoint of a Neuroimmunologist 102
Immunological Alterations in Alzheimer's Disease: Antimicroglia Antibodies in Sera of Alzheimer Patients 108
Author Index 114
Subject Index 115

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