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Lipids and the Kidney

Author: William F. Keane
Published: June 1997
Publisher: Karger, S. Inc.
ISBN: 3805563892
Hardcover Book
Number of Pages: 234
 
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Lipids and the Kidney


Table of Contents:


Preface
Lipid Abnormalities in Progressive Renal Insufficiency 1
Hypertension, Hyperlipidemia and Microalbuminuria 11
Apolipoprotein E Phenotype and Renal Disease 22
Lipoprotein Glomerulopathy and Its Pathogenesis 30
Cholesterol as a Predictor of Progression in Diabetic Renal Disease 39
Cholesterol as a Predictor of Progression in Nondiabetic Chronic Renal Disease 48
Role of Lipids in Chronic Renal Allograft Rejection 62
Effect of Lipid-Lowering Therapy on the Progression of Renal Disease in Nondiabetic Nephrotic Patients 68
Treatment of Hyperlipidaemia in Patients with Non-Insulin-Dependent Diabetes mellitus with Progressive Nephropathy 79
Effect of Antiproteinuric Treatment on the Lipid Profile in Nondiabetic Renal Disease 88
The Effect of HMG-CoA Reductase Inhibitors on Chronic Allograft Rejection 97
Long-Term Low-Density Lipoprotein Immunoapheresis in Renal Disease 105
Role of Lipids in Progressive Renal Disease: Insights from the Analbuminemic Rat 120
Hyperlipidemia and Tissue Contents of N-(Carboxymethyl)lysine in Streptozotocin Diabetes 132
Effect of Lipids on Glomerular Fibrinolysis in vitro 140
Effects of Lipoprotein (a) on Mesangial Cell Biology 146
HMG-CoA Reductase Inhibitor Suppression of Glomerular Cell PRoliferation in Rats with Anti-Thy-1.1 Nephritis 153
The Role of Oxidatively Modified Lipoproteins in Lipid Nephropathy 160
Effect of Low-Density Lipoproteins on Mesangial Cell Expression of Monocyte Chemoattractant Peptides 176
Regulation of Mesangial Cell Proliferation by the Mevalonate Pathway 191
Hypercholesterolemia and Progressive Kidney Disease: The Role of Macrophages and Macrophage-Derived Products 197
Central Role of the Transcription Factor Nuclear Factor-[kappa]B in Mesangial Cell Production of Chemokines 210
Isoprenoids, Ras and Proliferative Glomerular Disease 219
Author Index 228
Subject Index 229


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