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Table of Contents:

Introduction: II Florence Meeting on Advances in Cardiomyopathies 1
The Classification of Cardiomyopathies 3
Hypertrophic Cardiomyopathy
The Clinical Significance of Genetic Testing in Familial Hypertrophic Cardiomyopathy 17
The Italian Multicentric Study on Hypertrophic Cardiomyopathy: I. Natural History and Clinical Course of Unselected Patients 22
The Italian Multicentric Study on Hypertrophic Cardiomyopathy: II. Prognostic Assessment in Symptomatic Patients 28
Detection and Clinical Consequences of Myocardial Ischemia and Reduced Coronary Reserve 36
Identification and Management of High Risk Patients with Hypertrophic Cardiomyopathy 42
Hypertrophic Cardiomyopathy and Sudden Death in the Young: a Pathologist's View 51
The Clinicopathologic Spectrum of Hypertrophic Cardiomiopathy. The Experience of the Italian Heart Transplant Program 60
Medical Treatment Options in Hypertrophic Cardiomyopathy 70
DDD Pacing in Hypertrophic Cardiomyopathy: State of the Art 76
Indications and Outcome of Cardiac Surgery for Severely Symptomatic Patients with Hypertrophic Obstructive Cardiomyopathy 81
Dilated cardiomyopathy: Etiology, Pathophysiology and Clinical Data
Genetic Basis of Dilated Cardiomyopathy 89
Virus Infection in Cardiomyopathies: Brief Overview, Recent Advances 97
Organ-Specific Cardiac Autoantibodies in Dilated Cardiomyopathy: Pathogenetic Implications 101
Inflammatory Cardiomyopathy: Diagnostic and Therapeutical Options 107
Mitochondrial DNA Mutations and Cardiomyopathies 117
Pathophysiologic Role of Coronary Microcirculatory Impairment in Dilated Cardiomyopathy 128
Myocardial Catecholamines and Inotropic Response in Heart Muscle Disease 138
Molecular Biology of Heart Failure 147
Dilated Cardiomyopathy: Does Etiological Heterogeneity Portend Clinical Heterogeneity? 160
Recent Advances in Etiopathogenesis of Dilated Cardiomyopathy: Which Relevance for the Clinical Cardiologist? 171
The Italian Multicentric Study: Natural History of Dilated Cardiomyopathy 183
Mildly Dilated Cardiomyopathy 194
Dilated Cardiomyopathy: Treatment
Immunosuppressive Treatment for Inflammatory Dilated Cardiomyopathy (Myocarditis) 205
Prevention of Sudden Death in Patients with Dilated Cardiomyopathy 221
Medical Treatment of Heart Failure: Problems in Dilated Cardiomyopathy 229
Treatment of Dilated Cardiomyopathies with [beta]-adrenergic Blocking Agents 236
The role of [beta]-Blockers in the Management of Heart Failure: Results of Controlled Trials 245
Controversial Issues on [beta]-Blocker Treatment: Has Metoprolol an Additive Effect to Conventional Medical Treatment in Heart Failure Due to Dilated Cardiomyopathy? 254
[beta]-Blockers for Heart Failure: Practical Issues 262
DDD Pacing in Dilated Cardiomyopathy 274
End-Stage Heart Failure and Timing of Heart Transplantation 280
Cardiomyoplasty: Surgical Therapy for Ischemic and Idiopathic Dilated Cardiomyopathies 294
Left Ventricular Assist Device as Bridge to Transplantation 303
Subject Index 313